Expression of biologically active murine interleukin-18 inLactococcus lactis
نویسندگان
چکیده
منابع مشابه
Enhanced secretion of biologically active murine interleukin-12 by Lactococcus lactis.
The novel signal peptide SLPmod was used for the secretion of murine interleukin-12 (mIL-12) by Lactococcus lactis. A >4-fold increase in secretion was observed when SLPmod was used instead of the Usp45-derived secretion signal. Oral delivery of this cytokine using the autoinducible host L. lactis FI5876 utilizing SLPmod resulted in a significant increase in mIL-12 plasma levels in mice.
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2016
ISSN: 1574-6968
DOI: 10.1093/femsle/fnw234